One film is a vintage low-budget independent that has been called the greatest horror comedy of all time, the other is a brand new music documentary that has been hailed as “groundbreaking” and “revolutionary.”

This week, CinemaNiche returns to Studio Two Three with showings of two films that couldn’t be more different. On Oct. 10, the film series specializing in cult and music-related movies is slated to screen the acclaimed music doc, “Eno,” about the enigmatic musician and producer Brian Eno, while “Spider Baby,” the wild 1967 cult film from director Jack Hill, will be shown in a special Halloween fundraiser for Studio Two Three on Oct. 11.

“Eno” has been much anticipated, largely because of its unique presentation style. No two showings of “Eno” will be the same, says Jeff Roll, the founder and co-curator of CinemaNiche. “There is a different viewing each screening.” Mostly shy of talking heads, the film chiefly consists of archival clips and a one-on-one interview with the man himself, who has worked with everyone from U2 to Devo to, yes, Talking Heads.

Filmmaker Gary Nustwit and creative technologist Brendan Dawes have developed a generative software that creates unique sequences and edits, resulting in a film with many potential different variations. “It’s not unlike the kind of process that Eno himself uses in his art,” says Roll, referring to the producer’s vaunted “oblique strategies” method of using chance and randomness. Even though each version of this new documentary is different, Eno’s rich archive of hundreds of hours of never-before-seen footage, and unreleased music will be prominently featured.

“I have the feeling that 80% or 90% percent of the versions will be roughly the same,” says musician and DJ PJ Sykes, one of the film collective’s co-curators, along with Roll and Shane Brown, the Byrd Theatre’s projectionist. “It’s the little details that will be changed. Perhaps different musical clips or a change in editing.”

“I think of Eno as an art film about creativity,” director Gary Huswit says in a press statement, “with the output of Brian’s 50-year career as its raw material. What I’m trying to do is to create a cinematic experience that’s as innovative as Brian’s approach to music and art.” The screening is being sponsored by Plan 9 Music and, while sold out online, there may be overflow tickets available at the door on the night of the show.

The Oct. 11 screening of “Spider Baby” is a special Halloween event with proceeds going to Studio Two Three, says Roll. “We wanted to do something as a gift back to them, something unique that was made for the Halloween season. We asked ourselves, ‘What’s a good cult classic that’s not screened all the time, like ‘Night of the Living Dead’ or ‘Halloween’? ‘Spider Baby’ isn’t one you often see on the big screen.”

The black and white horror-comedy is the first feature from director Jack Hill, a frequent Roger Corman collaborator known for his grindhouse and exploitation films. “Hill is responsible for launching the career of Pam Grier.” says Roll. “He directed ‘Foxy Brown,’ and all of those women in prison movies.” Spider Baby was shot in 1964 on a budget of $55,000, he adds. “Even back then, that was pretty low-budget. But it inspired a lot of the horror films of the 70s, especially ‘The Texas Chainsaw Massacre.’ It’s more of a fun ride than a thrill ride.”

Opening the “Spider Baby” screening will be the Blood Ponies, a husband and wife duo, originally from San Diego, California, that Roll calls “the gothic White Stripes.” Sykes likens them to the Cramps. “We always want to set a mood for the screenings and they fit right in with the vibe.”

CinemaNiche has big plans for next year, when they hope to bring the new Butthole Surfers documentary to Studio Two Three, among other offerings. Sykes: “Richmond is cool and weird and I think there is support for the kinds of films we want to bring.”

“Eno” will screen at Studio Two Three on Thursday, Oct. 10. The event is sold out online. “Spider Baby” will screen with special guests the Blood Ponies on Oct. 11. Both films are $13. https://www.studiotwothree.org